Endocrine Abstracts

Introduction: Vitamin D, known mainly as a calcium-phosphorus homeostasis regulator, turned out to play also a significant role in the immune system modulation. Vitamin D deficiency has been reported in some autoimmune disorders. It is also suspected that polymorphisms of vitamin D-related genes comprise a risk factor for different autoimmune diseases. Therefore the aim of our study was to assess vitamin D receptor (VDR) gene FokI polymorphism in thyroid associated orbitopathy...

Introduction: Recent data showed that PCOS is related to abnormal calcium and phosphate metabolism. The patients are characterized by elevated levels of PTH and decreased levels of vitamin D. Abnormalities in mineral homeostasis are related to insulin resistance. In this study, we assessed a complex of calcium and phosphate metabolism indices in patients diagnosed with PCOS.Material and methods: 60 women, aged 25±5 years diagnosed with PCOS accordin...